spot based on ****** (ca.6.075×10 g) equals to (in order of magnitude) that based on ******-Ag
CNP samples (ca. 5.087×10 g). Similarly, the quantity of ****** lighted by the laser spot based on ****** (ca.1.944×10 g) equals to (in order of magnitude) that based on ******-Ag CNPs (ca. 1.717×10 g). Take the SERS detection of ****** for example: For the SERS detection of ****** based on ******-Ag CNPs, the probe volume is considered a focal [b]“tube” with a waist diameter of 90 ?m and a depth of ca. 1cm. By using the concentration of ****** (0.08%) one can determine the quantity of ****** molecules contributing to the Raman intensity ( (1000+60) ×10 ×0.08% × ? (45 ×10 ) ×1×10 / [(1000+60)×10 ] ~ 5.087×10 g). For the SERS detection of ****** based on ******, supposing that all the ****** molecules adsorbed on the surface of ****** evenly, one can determine the quantity of ****** molecules contributing to the Raman intensity (~ (50) ×10 ×1.5% × ? (45 ×10 ) / ? (5 ×10 ) ~ 6.075×10 g).
[b] L. Baia, K. Gigant, U. Posset, et al. Appl. Spectrosc, 56 (2002) 536.
(2) Response to comment: In the experimental results section does not appear how the SERS
measurements on ******-NPs were performed.
Response: We are very sorry for our negligence of introduce how the SERS measurements on ******-Ag CNPs were performed in the experimental results section. As Reviewer suggested that we have made complementarities of this experimental process in the section of 2.3 of the revised manuscript. (the section of 2.3, 16-20 lines)
(3) Response to comment: A significant comparison between the SERS activities of ******-NPs
and ****** substrates is not possible based on what reported in the paper. For instance, is t