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抗苗勒氏管激素(AMH)参考值解读
1、健康女性AMH水平:AMH与年龄呈负相关作用[1]。 年龄 <30 31–35 1.88-6.08 36–40 1.71-5.30 AMH值 AMH值低于相应年龄段正常参考值 AMH>8.40ng/ml,国外数据[2] AMH>6.99ng/ml,中信湘雅数据[3] 绝经 3、AMH预测卵巢反应性 卵巢反应性 预测低反应 预测高反应 4、健康男性参考值 年龄(岁) AMH值(ng/ml) 20-60 1.45-18.77 >60 0.34-9.38 AMH参考值 AMH<0.5-1.1ng/ml,中华医学会生殖医学分会《2015年 卵巢低反应专家共识》[5] AMH>3.36ng/ml,国外数据[6] AMH>4.17ng/ml,中山二院数据[7] AMH值低于检测下限[4] 41–45 0.78-3.56 46–50 0.76-2.80 AMH参考值 2.50-6.30 2、AMH与卵巢相关疾病 卵巢相关疾病 卵巢早衰(卵巢储备功能低下) 多囊卵巢综合征(PCOS)
参考文献
[1] La Marca A, Sighinolfi G, Giulini S, et al. Normal serum concentrations of anti-Mullerian hormone in women with regular menstrual cycles[J]. Reprod Biomed Online,2010,21(4):463-469; [2] Pigny, P; Jonard, S; Robert, Y, et al. Serum Anti-Müllerian Hormone as a Surrogate for Antral Follicle Count for Definition of the Polycystic Ovary Syndrome[J], Obstetrical & Gynecological Survey, 2006, 61(8):522-523;
[3] 熊紫薇, 胡坚, 陈薪宇等.抗缪勒氏管激素在多囊卵巢综合征诊断中的价值[J].分子影像学杂志,2015,38(2):80-83;
[4] Knauff E A, Eijkemans M J, Lambalk C B, et al. Anti-Mullerian hormone, inhibin B, and antral follicle count in young women with ovarian failure[J]. J Clin Endocrinol Metab,2009,94(3):786-792;
[5] 武学清, 孔蕊,田莉.卵巢低反应专家共识.生殖与避孕,2015,2: 71-79; [6] Lee TH, Liu CH, Huang CC, et al. Serum anti-mu¨llerian hormone and estradiol levels as predictors of ovarian hyperstimulation syndrome in assisted reproduction technology cycles[J]. Human Reproduction,2008,23(1):160–167;
[7] 谭嘉琦,陈晓莉,李予等. 抗苗勒管激素预测卵巢反应性的价值研究[J].实用妇产科杂志,2015,31(8):583-586.
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