2013
绾т笓涓氬瀷纭曞＋鐮旂┒鐢熴�婂尰瀛﹀疄楠屽姩鐗╁銆嬭�冩煡棰?
濮撳悕
瀛﹀彿
涓撲笟
鎴愮哗
涓�銆佸悕璇嶈В閲?/p>
1.AEIR
鈥?/p>
AEIR
鈥?/p>
鏄敓鍛界瀛︾爺绌舵墍蹇呴渶鐨勫洓涓熀鏈潯浠躲�?/p>
鈥?/p>
A
鈥?/p>
鍗?/p>
animal
锛堝疄楠屽姩鐗╋級
鈥?/p>
E
鈥?/p>
绯?/p>
equipment
锛堣澶囷級
鈥?/p>
I
鈥濅负
information
锛堜俊鎭級
鈥?/p>
R
鈥濇槸
reagent
锛堣瘯鍓傦級
2.3R
鈥?/p>
3R
鈥?/p>
锛屽嵆鍑忓皯锛?/p>
reduction
锛?/p>
銆佷唬鏇?/p>
(replacement)
鍜屼紭鍖?/p>
(refinement)
鍘熷垯銆?/p>
3.SPF
鍔ㄧ墿
鏃犵壒瀹氱梾鍘熶綋鍔ㄧ墿
( specific pathogen free animal, SPF)
鎸囧湪娓呮磥鍔ㄧ墿鐨勫熀纭�涓婏紝
瑕佹眰涓嶆惡甯﹀彲
鑳藉共鎵板疄楠岀殑鐗瑰畾鐥呭師浣撳拰瀵勭敓铏缁胯創鏉嗚弻绛夈�?/p>
SPF
鍔ㄧ墿鐨勭缇ゆ潵婧愪簬鏃犺弻鍔ㄧ墿锛?/p>
楗插吇浜?/p>
灞忛殰绯荤粺涓紝瀹炴柦涓ユ牸鐨勫井鐢熺墿鍜屽瘎鐢熻櫕鎺у埗銆備娇鐢?/p>
SPF
鍔ㄧ墿锛屽湪瀹為獙涓彲浠ュ畨鍏ㄥ彲闈犲湴
鎺掗櫎鍔ㄧ墿鎵�鎼哄甫鐥呭師浣撳強鐗瑰畾寰敓鐗╃殑骞叉壈銆?/p>
SPF
鍔ㄧ墿浣滀负鍥介檯鍏鐨勬爣鍑嗗疄楠屽姩鐗╋紝
鍙�?/p>
鐢ㄤ簬鎵�鏈夌鐮斿疄楠屻�傝绾у姩鐗╁仴搴凤紝绻佹畺鐜囬珮锛岃嚜鐒舵浜＄巼浣庛�?/p>
4.
姝ご鐥?/p>
鑲烘敮鍘熶綋鍙紩璧峰寲鑴撴�ч蓟鐐庡拰鎱㈡�ц偤鐐庣瓑鍛煎惛绯荤粺鐤剧梾锛?/p>
鏈夋椂骞跺彂涓�崇値銆?/p>
鍐呰�崇値寮曡捣瀹為獙
鍔ㄧ墿鈥滄澶寸梾鈥?/p>
锛屾偅榧犲ご鏂滀簬鎮ｄ晶杞湀璧帮紝鎻愯捣榧犲熬浣夸箣鍊掔珛锛屾偅榧犺韩浣撹繀閫熸棆杞�傝偤鏀師
浣撴劅鏌撶敓娈栭亾鍙鑷存鑳庡拰涓嶈偛銆?/p>
5.
灏侀棴缇ゅ姩鐗?/p>
鍙堢О杩滀氦缇わ紙
out bred stock
锛夊姩鐗┿�傛寜鍥介檯瀹為獙鍔ㄧ墿绉戝濮斿憳浼氱殑瀹氫箟锛屾槸鎸囦互闈炶繎浜蹭氦閰?/p>
鏂瑰紡绻佹畺鐢熶骇鐨勪竴涓缇わ紝
鍦ㄤ笉浠庡閮ㄥ紩鍏ユ柊琛�缂樼殑鏉′欢涓嬶紝
鑷冲皯杩炵画绻佹畺
4
浠ｄ互涓婄殑鍔ㄧ墿銆?/p>
濡傛槅鏄庣灏忛紶銆?/p>
SD
澶ч紶绛夈�傜壒鐐癸細绻佹畺鐜囬珮锛岄噸澶嶆�у樊銆?/p>
浜屻�佺畝绛旈
1.
浠�涔堟槸杩戜氦绯诲姩鐗╋紵绠�杩拌繎浜ょ郴鍔ㄧ墿鐨勭壒鐐广�?/p>
浠庝竴涓姩鐗╃兢浣撲腑閫夌敤琛�缂樻瘮杈冩帴杩戠殑闆岄泟涓綋锛?/p>
鍗虫湁鍏卞悓绁栧厛鐨勫厔濡广�?/p>
姣嶅瓙銆?/p>
鐖跺コ杩涜浜?/p>
閰嶏紝姝ょ杩戜翰浜ら厤鐨勬柟寮忕О涓鸿繎浜ゃ�傚叏鍚岃優鍏勫涔嬮棿鎴栦翰浠ｄ笌瀛愪唬涔嬮棿杩炵画浜ら厤绻佹畺杈惧埌
20
浠ｄ互涓婄殑鍔ㄧ墿锛岀О涓鸿繎浜ょ郴鍔ㄧ墿銆?/p>
杩戜氦绯诲姩鐗╃殑鐗圭偣锛氥垹
鍩哄洜绾悎鎬э紙
homozygosity
锛?/p>
锛屻垺
閬椾紶缁勬垚鐨勫悓婧愭�э紙
isogenicity
锛?/p>
锛?/p>
銏?/p>
琛ㄧ幇鍨嬬殑涓�鑷存�э紙
uniformity
锛?/p>
锛屻垼
瀵瑰鐣屽洜绱犵殑鏁忔劅鎬э紙
sensitivity
锛?/p>
锛屻垽
閬椾紶鐗瑰緛鐨勫彲
杈╁埆鎬э紙
identifiably
锛?/p>
锛屻垾
閬椾紶缁勬垚鐙壒鎬э紙
individuality
锛?/p>
锛屻垿
鑳屾櫙璧勬枡鍙煡鎬э紝銏?/p>
鍥介檯
鍒嗗竷骞挎硾鎬?/p>
2.
鈥?/p>
DBA/1fLACA/Lac
灏忛紶鈥?/p>
涓嫳鏂囧瓧姣嶃�?/p>
绗﹀彿鍜屾暟瀛楃殑娑典箟鏄粈涔堬紵
DBA
涓哄皬榧犺繎浜ょ郴鍚嶇О锛?/p>
1
琛ㄧず浜氱郴锛?/p>
f
琛ㄧず浠ｄ钩锛?/p>
LACA
涓轰唬涔虫瘝榧犵殑鍝佺郴锛?/p>
Lac
浠ｈ〃鍩?