铔嬬櫧璐ㄥ寲瀛?- 鐧惧害鏂囧簱

鏂板缓

涓婁紶

棣栭〉

鍔╂墜

鏈�杩?/div>

璧勬枡搴?/div>

宸ュ叿

1- 

铔嬬櫧璐ㄥ寲瀛?/p>

 

 

鍚嶈瘝瑙ｉ噴

 

锛堜竴锛?/p>

   

涓ゆ�х�诲瓙锛�

dipolarion

锛変笌涓ゆ�у寲鍚堢墿

 

锛堜簩锛?/p>

   

绛夌數鐐?/p>

(isoelectric point,pI)

涓庣瓑绂诲瓙鐐?/p>

 

锛堜笁锛?/p>

   

蹇呴渶姘ㄥ熀閰革紙

essential amino acid

锛?/p>

 

锛堝洓锛?/p>

   

绋�鏈夋皑鍩洪吀

(rare amino acid) 

锛堜簲锛?/p>

   

闈炶泲鐧借川姘ㄥ熀閰?/p>

(nonprotein amino acid) 

 

锛堝叚锛?/p>

   

鏋勫瀷

(configuration)

涓庢瀯璞?/p>

(conformation) 

锛堜竷锛?/p>

   

鑲介敭銆佽偨骞抽潰銆佽偨鍗曚綅銆佸�氳�?/p>

  

 

锛堝叓锛?/p>

   

N

鏈�绔�涓?/p>

C

鏈�绔�

 

锛堜節锛?/p>

   

铔嬬櫧璐ㄧ殑涓�绾х粨鏋?/p>

(protein primary structure) 

锛堝崄锛?/p>

   

铔嬬櫧璐ㄧ殑浜岀骇缁撴瀯

(protein secondary structure)  

 

锛堝崄涓�锛?/p>

              

铔嬬櫧璐ㄧ殑

伪

锛嶈灪鏃嬬粨鏋?/p>

 

锛堝崄浜岋級

              

铔嬬櫧璐ㄧ殑

尾

锛嶆姌鍙犵粨鏋?/p>

 

锛堝崄涓夛級

              

缁撴瀯鍩?/p>

(domain) 

锛堝崄鍥涳級

              

瓒呬簩绾х粨鏋?/p>

(super-secondary structure) 

锛堝崄浜旓級

              

铔嬬櫧璐ㄧ殑涓夌骇缁撴瀯

(protein tertiary structure) 

 

锛堝崄鍏�锛�

              

铔嬬櫧璐ㄧ殑鍥涚骇缁撴瀯

(protein quaternary structure) 

锛堝崄涓冿級

              

瀵¤仛浣擄紙

multimeric protein

锛変笌浜氬熀锛?/p>

subunit

锛?/p>

 

锛堝崄鍏�锛�

              

姘㈤敭

(hydrogen bond) 

銆佺�诲瓙閿�

(ionic bond)

銆侊紟

 

锛堝崄涔濓級

              

鐤忔按鐨勭浉浜掍綔鐢?/p>

 

(hydrophobic interaction)

銆佽寖寰峰崕鍔?/p>

( van der Waals force) 

锛堜簩鍗侊級

              

绠�鍗曡泲鐧戒笌缁撳悎铔嬬櫧

 

锛堜簩鍗佷竴锛?/p>

       

绯栬泲鐧戒笌鑴傝泲鐧?/p>

 

 

锛堜簩鍗佷簩锛?/p>

       

鐩愭瀽

(salting out)

涓庣洂婧?/p>

(salting in)