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http://www.qikan.com.cn
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浣滆�咃細鐩涙櫠
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2011
骞寸
08
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[
鎽樿
]
鐩殑
瑙傚療鑳歌厰鍐呮敞灏勫杈鹃搨娌荤枟鎭舵�ц兏鑵旂Н娑茬殑涓村簥鐤楁晥鍙婂畨鍏ㄦ�с�?/p>
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1
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34
渚嬪杈鹃搨
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娆★紝
0.9%
姘寲閽犳敞灏勬恫
40mL
绋�閲婏紱瀵圭収缁?/p>
25
渚嬶紝椤洪搨
80mg/
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0.9%
姘寲閽犳敞灏勬恫
40mL
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1
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3
娆°�?/p>
缁撴灉
娌荤枟缁?/p>
CR 12
渚嬶紝
PR 14
渚嬶紝鏈夋晥鐜囦负
76.5%
锛涘鐓х粍
CR 4
渚嬶紝
PR 9
渚嬶紝鏈夋晥鐜囦负
52.0%
銆備袱缁勬瘮杈冨樊寮傛湁缁熻瀛︽剰涔夛紙
P
锛?/p>
0.05
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[
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]
濂堣揪閾傦紱鎭舵�ц兏鑵旂Н娑诧紱鐤楁晥
[
涓浘鍒嗙被鍙?/p>
] R730.5[
鏂囩尞鏍囪瘑鐮?/p>
] B [
鏂囩珷缂栧彿
] 2095-0616
锛?/p>
2011
锛?/p>
08-83-02
Therapeutic Effect of Nedaplatin in the Treatment of M alignant Hydrothorax
SHENG Jing
Department of Oncology
锛?/p>
Nanyang Central Hospital
锛?/p>
Nanyang 473000
锛?/p>
China
[Abstract] Objective To study the efficacy of nedaplatin
锛?/p>
NDP
锛?/p>
in the treatment of m alignant
hydrothorax. Methods 59 patients with m alignant hydrothorax used disposable single lumen central
venous catheter do chest puncture catheter and close-type drainage of row after all hydrothorax is
drain
锛?/p>
injection drug in the thoracic cavity. The patients were divide into 2 groups. One group of 34
patients were treated with NDP
锛?/p>
100mg
锛?/p>
diluted to 40
锝?/p>
50mL with NS
锛?/p>
The other group of 25
patients were treated with DDP
锛?/p>
80mg
锛?/p>
diluted to 40mL with NS. They were respectively injected
into pleural cavity. According to the illness
锛?/p>
the medicine would be injected after 5
锝?/p>
7 days
锛?/p>
the
totalize is less than 3 times. Results In the NDP's group
锛?/p>
the complete remission are 12 cases
锛?/p>
the
partial remission are 14 cases
锛?/p>
the response rates was 76.5%
锛?/p>
in the DDP鈥檚 group
锛?/p>
there were 4
cases of complete remission
锛?/p>
9 cases with partial remission
锛?/p>
the response rates was 52.0%. Two
groups of comparative difference were statistically significant
锛?/p>
P
锛?/p>
0.05
锛?/p>
. There were light in toxic