銆婅鐭ョ缁忕瀛︺�嬫湡鏈涔?/p>
涓�銆佹璁?/p>
1.
浠�涔堟槸璁ょ煡绁炵粡绉戝锛?/p>
[ppt]
璁ょ煡绁炵粡绉戝鏄槓鏄庤鐭ユ椿鍔ㄧ殑蹇冪悊杩囩▼鍜岃剳鏈哄埗鐨勭瀛︺�傚叾鐮旂┒妯″紡鏄皢琛屼负銆佽鐭ヨ繃绋嬨�佽剳鏈哄埗涓夎�呮湁
鏈哄湴缁撳悎璧锋潵锛岀畝鑰岃█涔嬶紝瀹冩槸鐮旂┒鑴戝浣曞垱閫犵簿绁炵殑銆?/p>
浜?/p>
.
鏂规硶锛?/p>
2.
缁撴瀯纾佸叡鎸垚鍍忕殑绌洪棿
contrast
涓庡姛鑳藉叡鎸垚鍍忕殑鏃堕棿
contrast
鐨勬蹇?/p>
缁撴瀯鍍忕殑绌洪棿
contrast
锛氱粨鏋勫儚涓�鑸涓烘槸姣旇緝鍥哄畾鐨勶紝鍦ㄧ煭鏃堕棿鍐呬笉浼氬彉鍖栵紝鎵�浠ョ┖闂?/p>
contrast
鏄璇曢棿鏌愪釜
鑴戝尯
volume
澶у皬鐨?/p>
contrast
锛?/p>
鍔熻兘鍍忕殑鏃堕棿
contrast
锛氬姛鑳藉儚鍦ㄦ椂闂寸淮搴︿笂鏄彉鍖栫殑锛屼娇鐢?/p>
block
design/event
related
design
鏃讹紝鍙互鍦ㄨ
璇曞唴鍋氭椂闂翠笂鐨?/p>
experimental
condition
vs.
baseline
鐨?/p>
contrast
锛屽綋鐒跺湪杩欎箣鍚庝篃鍙互鍋氳璇曢棿鐨勪袱涓椂闂翠笂
鐨?/p>
experimental condition vs. baseline
鐨?/p>
contrast
鐨?/p>
contrast
銆?/p>
3.
fMRI
鐮旂┒涓殑澶氶噸姣旇緝鏍℃鐨勬蹇点�備负浠�涔堥渶瑕佸仛澶氶噸姣旇緝锛熷父鐢ㄧ殑鐭鏂规硶鏈夊摢浜涳紙鍒椾妇
3
涓乏鍙筹級锛?/p>
锛堢瓟妗?/p>
1
锛氬湪鎴戜滑杩涜
voxel-by-voxel
姣旇緝鏃讹紝鐢变簬姣旇緝娆℃暟寰堝锛岄偅涔堢姱
I
鍨嬮敊璇殑鏁伴噺涔熼殢涔嬪鍔狅紝濡傛灉杩樹互
鍙繘琛屼竴娆℃瘮杈冪殑
伪
鍊间负鐘?/p>
I
鍨嬮敊璇殑姒傜巼鐨勮瘽锛屽氨浼氬嚭鐜板亣闃虫�х殑缁撴灉锛屾墍浠ョ悊璁轰笂姣旇緝娆℃暟澶т簬
1
娆＄殑鍒嗘瀽
閮藉簲璇ヨ繘琛屽閲嶆瘮杈冩牎姝ｃ�傚彟澶栵紝鍦?/p>
fMRI
鏁版嵁鍒嗘瀽涓紝鎴戜滑鐩镐俊鑴戠殑娲诲姩搴旇鍦ㄧ伆璐ㄧ殑涓�瀹氳寖鍥村唴锛岃�屼笉鏄粎鍦?/p>
涓�涓?/p>
voxel
鍐咃紝
鎵�浠ラ�氳繃澶氶噸姣旇緝鏍℃鎴戜滑鍙互鎶婅繖浜涘崟涓殑鍋囬槼鎬?/p>
voxel
鎺掗櫎銆?/p>
fMRI
鏁版嵁鍒嗘瀽涓父鐢ㄧ殑澶氶噸姣旇緝
鏍℃鏈?/p>
FDR
锛?/p>
false discovery rate
锛?/p>
锛?/p>
FWE
锛?/p>
family-wise error
锛夊拰
AFNI
鎻愪緵鐨勬牎姝ｆ柟娉曘�?/p>
锛?/p>
4.
鍦ㄧ鍏辨尟鎴愬儚涓殑琛�娑插姩鍔涘鍝嶅簲鍑芥暟鎸囩殑鏄粈涔堬紵
琛�娑插姩鍔涘鍝嶅簲鍑芥暟鍙楀尯鍩熸�ц剳琛�娴?/p>
锛?/p>
rCBF
锛?/p>
銆?/p>
琛�浣撶Н
锛?/p>
rCBV
锛?/p>
绛夌殑鍙樺寲褰卞搷锛?/p>
鏄殢鐫�鍒烘縺鍑虹幇浠庡钩绋崇姸鎬佸厛闄嶄綆锛?/p>
鍐嶅崌楂橈紝鍐嶉檷浣庯紝鏈�鍚庢仮澶嶅埌骞崇ǔ鐘舵�佺殑涓�鏉″嚱鏁版洸绾裤�?/p>
5.
浠�涔堟槸鎴愬儚璁惧鐨勭┖闂村垎杈ㄧ巼涓庢椂闂村垎杈ㄧ巼锛?/p>
杩欎袱涓垎杈ㄧ巼閮藉簲璇ユ寚璁惧杩涜鍔熻兘鎴愬儚鐨勬弿杩般�?/p>
绌洪棿鍒嗚鲸鐜囷紙
Spatial
Resolution
锛夋槸鎸囨垚鍍忚澶囧湪浠�涔堢┖闂存按骞充笂鍙嶆槧澶ц剳娲诲姩鐨勪俊鍙凤紝涔熷氨鏄兘鍦ㄤ粈涔堟牱鐨勭┖
闂存按骞充笂鍒嗚鲸鍑轰笉鍚岀殑淇″彿鐨勫彉鍖栵紝鍙互鍙嶆槧涓虹獊瑙︾骇锛岀缁忓厓绾э紝
voxel
绾э紝鑴戝洖绾х瓑绌洪棿鍒嗚鲸鐜囥�?/p>
鏃堕棿鍒嗚鲸鐜?/p>
锛?/p>
Temporal
Resolution
锛?/p>
鏄寚鎴愬儚璁惧鍦ㄨ剳娲诲姩鍚庡闀挎椂闂村唴鑳借褰曚笅娲诲姩淇″彿锛?/p>
鍙互鍙嶆槧涓烘绉?/p>
锛?/p>
ms
锛?/p>
绾э紝绉掞紙
m
锛夌骇锛屽垎閽燂紙
min
锛夌骇锛屽皬鏃讹紙
h
锛夌骇绛夋椂闂村垎杈ㄧ巼锛?/p>
绌洪棿鍒嗚鲸鐜囷細鍗曠粏鑳炶褰?/p>
>
棰呭唴
ERPs >
棰呭
ERPs
銆?/p>
fMRI
銆?/p>
PET
銆?/p>
鏃堕棿鍒嗚鲸鐜囷細
MEG
銆侀澶?/p>
ERPs > fMRI
銆?/p>
TMS
銆?/p>
PET
銆?/p>
6. BOLD-fMRI, NIRS, EEG/ERP
杩欎笁绉嶆垚鍍忓悇鑷殑鐗圭偣鏄粈涔堬紵鍝袱涓箣闂村彲浠ュ悓鏃惰褰曪紝濂藉鍦ㄥ摢閲岋紵
BOLD-fMRI
鍒╃敤琛�娑蹭腑姘у悎琛�绾㈣泲鐧戒笌鍘绘哀琛�绾㈣泲鐧界殑纾佹晱鎰熸�т笉鍚岃繖涓�鐗圭偣锛屽绁炵粡娲诲姩鎵�寮曡捣鐨勮姘у彉鍖栬繘琛?/p>
鎴愬儚锛?/p>
fNIRS
鍒╃敤琛�娑蹭腑姘у悎琛�绾㈣泲鐧戒笌鍘绘哀琛�绾㈣泲鐧藉杩戠孩澶栧厜鐨勫厜鍚告敹绋嬪害鐨勪笉鍚岋紝瀵圭缁忔椿鍔ㄦ墍寮曡捣鐨勮姘?/p>
鍙樺寲杩涜鎴愬儚锛?/p>
EEG/ERP
璁板綍澶ц剳绁炵粡娲诲姩鎵�寮曡捣鐨勭數浣嶅彉鍖栬繘琛屾暟鎹噰闆嗐�傝繖涓夌闈炰镜鍏ョ殑鎴愬儚鏂瑰紡鍏锋湁鍚勮嚜鐨?/p>
浼樺姡锛?/p>
fMRI
鍏锋湁杈冮珮鐨勭┖闂村垎杈ㄧ巼锛屽彲浠ュ鑴戝尯杩涜鐩稿鍑嗙‘鐨勫畾浣嶏紝鍚屾椂鍏锋湁鐩歌緝浜?/p>
PET
鏇撮珮鐨勬椂闂村垎杈ㄧ巼锛屼絾
绉掔骇鐨勬椂闂村垎杈ㄧ巼鐩歌緝
fNIRS
鍜?/p>
EEG/ERP
杈冧綆锛屼笌蹇冭烦銆佸懠鍚哥瓑鐢熺悊鍣０淇″彿鍦ㄩ鍩熶笂鍙戠敓娣峰彔锛屽洜姝ゅ共鎵板鐪熷疄
绁炵粡娲诲姩鐨勬娴嬶紱
fNIRS
鍏锋湁鐧炬绉掔骇鐨勬椂闂村垎杈ㄧ巼锛?/p>
浠ュ強杈冧箣
EEG/ERP
鏇撮珮鐨勭┖闂村垎杈ㄧ巼锛?/p>
涓?/p>
fMRI
鐨勭┖闂村垎杈ㄧ巼
鐩歌繎锛屼絾绌洪棿瀹氫綅涓嶇敋鍑嗙‘锛?/p>
fNIRS
杩涜鏁版嵁閲囬泦鐩稿渚挎嵎锛屽疄楠屽噯澶囪緝涓虹畝鍗曪紝鍏锋湁鏇撮珮鐨勬槗鐢ㄦ�э紱
EEG/ERP
璁?/p>
褰曠缁忔椿鍔ㄧ殑鐢典綅鍙樺寲鎯呭喌锛岃�岄潪
fMRI
鍜?/p>
fNIRS
鍙兘璁板綍鐢辩缁忔椿鍔ㄥ紩璧风殑琛�姘у彉鍖栨儏鍐碉紝鍥犳鍦ㄧ爺绌剁缁忔椿鍔?