鎵撴槦鍙风殑涓嶆槸鐗圭‘瀹氫細鑰冪殑锛?/p>
鏄寰楀ぇ姒備笉
浼氳�冪殑
= =a
绗竴绔?/p>
缁嗚優鐨勬璁?/p>
鍖诲缁嗚優鐢熺墿瀛?/p>
(Medical cell biology)
锛?/p>
浠ョ粏鑳炵敓鐗╁鍜屽垎瀛愮敓鐗╁涓哄熀纭�锛?/p>
鎺㈢储鐮旂┒浜轰綋缁?/p>
鑳炲彂鐢熴�佸彂鑲层�佸娈栥�佽“鑰併�佹浜′互鍙婄粏鑳炵粨鏋勪笌鍔熻兘鐨勫紓甯镐笌浜虹被鐤剧梾鍏崇郴鐨勫绉戙�?/p>
缁冧範鍐?/p>
P9/
浜?/p>
/1
绗簩绔?/p>
缁嗚優鑶滀笌鐗╄川杩愯緭
鑶滆浆杩愯泲鐧?/p>
(membrane transport protein)
锛?/p>
缁嗚優鑶滀腑鐨勪竴绫诲叿鏈夎浆杩愬姛鑳界殑璺ㄨ啘铔嬬櫧銆傝啘杞?/p>
杩愯泲鐧藉彲鍒嗕负杞戒綋铔嬬櫧鍜岄�氶亾铔嬬櫧涓ょ被锛?/p>
杞戒綋铔嬬櫧鏃粙瀵艰鍔ㄨ繍杈撳張浠嬪涓诲姩杩愯緭锛?/p>
閫氶亾铔?/p>
鐧戒粎浠嬪琚姩杩愯緭銆?/p>
杞戒綋铔嬬櫧
(carrier protein)
锛?/p>
鏅亶瀛樺湪浜庣敓鐗╄啘涓婄殑澶氭璺ㄨ啘铔嬬櫧鍒嗗瓙锛屼笌琚浆杩愮墿璐ㄧ壒寮傛�?/p>
缁撳悎锛?/p>
寮曡捣杞戒綋铔嬬櫧鏈韩鏋勮薄鐨勬敼鍙橈紝浠嬪鐗╄川鐨勮法鑶滆浆杩愩�?/p>
鏃㈠彲浠嬪涓诲姩杞繍锛?/p>
鍙堝彲浠嬪
琚姩杞繍銆?/p>
绂诲瓙娉?/p>
(ionic pump)
锛?/p>
缁嗚優鑶滀笂瀛樺湪鐨勮兘瀵规煇绉嶇瀛愯繘琛屼富鍔ㄨ浆杩愮殑璺ㄨ啘铔嬬櫧銆?/p>
瀹冧滑鍏锋湁
ATP
閰剁殑娲绘�э紝
鍙互閫氳繃姘磋В
ATP
鑾峰彇鑳介噺锛岄�嗘祿搴︽搴﹁浆杩愭煇绉嶇瀛愯繘鍑虹粏鑳烇紝
濡傞挔閽炬车锛?/p>
閽?/p>
娉电瓑銆?/p>
鍙椾綋浠嬪鐨勮優鍚炰綔鐢?/p>
(recepter-mediated endocytosis)
锛?/p>
琚浆杩愮殑澶у垎瀛愪笌缁嗚優琛ㄩ潰鐨勭壒寮傛�?/p>
鍙椾綋缁撳悎锛?/p>
缁忚繃鏈夎灏忕獫鐨勫唴鍖栬�屾憚鍙栫墿璐ㄧ殑褰㈠紡锛?/p>
鏄竴绉嶉�夋嫨鎬х殑娴撶缉鏈哄埗銆?/p>
鍏剁壒鐐规湁鐗?/p>
寮傛�э紝楂樻晥鎬э紝閫夋嫨鎬э紝楂樺害娴撶缉銆?/p>
鍏朵綑缁冧範鍐?/p>
P21
/
1
銆?/p>
5
P23
/1
銆?/p>
2
銆?/p>
3
绗笁绔?/p>
缁嗚優鍐呰啘绯荤粺
淇″彿鑲?/p>
(signal
peptide)
锛?/p>
鐢变俊鍙峰瘑鐮佺炕璇戝嚭鐨勪竴娈电敱
18-30
涓枏姘存皑鍩洪吀缁勬垚鐨勮偨閾撅紝浣嶄簬
澶栬緭铔嬬櫧鐨?/p>
N-
绔紝鍙寚瀵煎杈撹泲鐧藉湪绮楅潰鍐呰川缃戜笂鍚堟垚锛屼竴鏃﹁繘鍏ュ唴璐ㄧ綉鑵斿嵆琚垏闄ゃ�?/p>
淇″彿鑲借瘑鍒绮?/p>
(signal recognition particle)
锛?/p>
鍦ㄧ粏鑳炲熀璐ㄤ腑瀛樺湪淇″彿鑲借瘑鍒绮?/p>
(SRP),
瀹冩槸鐢?/p>
6
涓鑲戒簹鍗曚綅鍜屼竴涓皬鐨?/p>
7SRNA
鍒嗗瓙缁勬垚銆?/p>
瀹冨彲鍏堣瘑鍒俊鍙疯偨骞朵笌涔嬬粨鍚堬紝
鐒跺悗灏嗕俊鍙疯偨
-
鏍哥硸浣撳鍚堜綋甯﹀埌鍙︿竴涓笌鍏惰瘑鍒殑绮楅潰鍐呰川缃戣啘涓婄殑鍋滈潬铔嬬櫧涓婏紝浠庤�屼娇澶栬緭铔嬬櫧鐨勫悎
鎴愯揪鍒板畾浣嶇殑鐩殑銆?/p>