9
涓灑绁炵粡绯荤粺鑽墿
绗竴鑺?/p>
闀囬潤鍌湢鑽?/p>
鑽悕
寮傛垔宸存瘮濡?/p>
(Amobarbital )
缁撴瀯涓庡寲瀛﹀悕
5-
涔欏熀
-5-(3-
鐢插熀涓佸熀
)-2
锛?/p>
4
锛?/p>
6-
锛?/p>
1
H
锛?/p>
3
H
锛?/p>
5
H
锛夊槯鍟朵笁閰?/p>
绫诲瀷
宸存瘮濡ョ被銆佺幆涓欎簩閰拌劜锛堝反姣斿Ε閰革級鐨勮鐢熺墿
鐗╃悊鎬ц川
鐧借壊缁撴櫠鎬х矇鏈?/p>
鍖栧鎬ц川
寮遍吀鎬?/p>
(pKa
涓?/p>
7.8)
鍙仛鎴愰挔鐩愪綔娉ㄥ皠鐢紱
姘磋В鎬э細鍏堕挔鐩愭按婧舵恫鏀剧疆鏄撴按瑙ｏ紝鏁呮湰绫昏嵂鐗╃殑閽犵洂娉ㄥ皠娑插簲鍋氭垚绮夐拡鍓傦紝涓寸敤鍓?
閰嶅埗銆?/p>
閴村埆鍙嶅簲
涓庣閰搁摱璇曟恫浣滅敤
-
鐢熸垚閾剁洂娌夋穩锛屾矇娣�婧朵簬杩囬噺姘ㄨ瘯娑蹭腑
涓庡悺鍟跺拰纭吀閾滄憾娑蹭綔鐢?/p>
-
鐢熸垚绱摑鑹茬粶鐩?/p>
浣撳唴浠ｈ阿
鑲濊剰锛?/p>
50
锛呯緹鍩哄寲鍚庡啀涓庤憽钀勭硸閱涢吀鍖栧悎鐗╃粨鍚堬紝缁忚偩鎺掑嚭
鑽墿鐢ㄩ�?/p>
涓晥鍌湢鑽?/p>
鍚堟垚
R1 =
寮傛垔鍩?/p>
锛?/p>
R2 =
涔欏熀
宸存瘮濡ョ被鏋勬晥鍏崇郴锛?/p>
1
锛庝笝浜岄叞鑴茬殑琛嶇敓鐗╋紝
5
浣嶇⒊鍘熷瓙鐨勬�绘暟鍦?/p>
4-8
锛岃嵂鐗╂湁閫傚綋鐨勮剛婧舵�э紝鏈夊埄浜庤嵂鏁堝彂鎸ャ�傜⒊鏁拌秴杩?/p>
8
锛?/p>
鍏锋湁鎯婂帴浣滐紱
2
锛庡紩鍏ヤ翰鑴傚熀鍥紝灏?/p>
C-2
涓婄殑姘т互纭唬鏇匡紝纭柗濡ラ挔閰告�ч檷浣庯紝鑴傛憾鎬у澶э紝璧锋晥蹇�佺煭銆?/p>
3
锛庡湪閰颁簹鑳烘爱寮曞叆鐢插熀锛屼篃鍙檷浣庨吀鎬у拰澧炲姞鑴傛憾鎬э紝璧锋晥蹇紱涓や釜姘笂閮藉紩鍏ョ敳鍩猴紝浜х敓鎯婂帴銆?/p>
鑻反姣斿Ε锛?/p>
5-
涔欏熀
-5-
鑻熀
-2,4
锛?/p>
6-
锛?/p>
1H
锛?/p>
3H
锛?/p>
5H
锛夊槯鍟朵笁閰?/p>
鑻反姣斿Ε鐨勭敤娉?/p>
闀囬潤
鍌湢
楹婚唹
鍙ｆ湇
鍙ｆ湇
鑲屾敞
0.015-0.03g
0.03-0.09g
0.1-0.2g
涓�鏃ヤ笁娆?/p>
鐫″墠鏈?/p>
鏈墠
1/2-1
灏忔椂
娉ㄦ剰浜嬮」锛?/p>
1.
涔呯敤鑳芥垚鐦?/p>
2.
鑲濆姛鑳戒弗閲嶅噺閫�鑰呮厧鐢ㄣ�?/p>
3.
娉ㄥ皠鍓傜敤娉ㄥ皠鐢ㄦ按閰嶆垚
5-10
锛呮憾娑诧紝鐜伴厤鐜扮敤銆傞潤娉ㄥ疁缂撴參銆傜粰鑽繃绋嬩腑搴旀敞鎰忚瀵熺梾浜虹殑鍛煎惛
鍙婅倢鑲夋澗寮涚▼搴︼紝浠ユ伆鑳芥姂鍒舵儕鍘ヤ负瀹溿�?/p>