榫欐簮鏈熷垔缃?/p>
http://www.qikan.com.cn
澶ц剳鑳惰川鐦ょ梾涓庡崟绾柋鐤圭梾姣掓�ц剳鐐庨壌鍒瘖
鏂?/p>
浣滆�咃細鐜嬪缓鍐?/p>
瀛?/p>
鐐?/p>
浜庢槬姹?/p>
鏉ユ簮锛氥�婁腑鍥界幇浠ｅ尰鐢熴�?/p>
2009
骞寸
33
鏈?/p>
[
鍏抽敭璇?/p>
]
澶ц剳鑳惰川鐦ょ梾
;
鍗曠函鐤辩柟鐥呮瘨鎬ц剳鐐?/p>
;
璇婃不娴佺▼
[
涓浘鍒嗙被鍙?/p>
] R739.4 [
鏂囩尞鏍囪瘑鐮?/p>
] A [
鏂囩珷缂栧彿
] 1673-9701(2009)33-08-03
澶ц剳鑳惰川鐦ょ梾
(gliomatosis cerebri,GC)
鏄竴绉嶅皯瑙佺殑浠ョ缁忚兌璐ㄧ粏鑳炲讥婕�х槫鏍峰鐢熶负鐗瑰緛
鐨勪腑鏋㈢缁忕郴缁熷師鍙戣偪鐦ゆ�х柧鐥?/p>
,
灞炰簬绁炵粡涓婄毊鑲跨槫鐨勪竴绉嶇壒娈婄被鍨?/p>
,
鐢?/p>
Nevin[1]
浜?/p>
1938
骞撮鍏?/p>
鎶ラ亾
,
鐢变簬鍏跺彂鐥呯巼杈冧綆
,
鍗犲悓鏈熺缁忎笂鐨偪鐦ょ殑
0.66%,
涓村簥琛ㄧ幇缂轰箯鐗瑰紓鎬?/p>
,
甯稿鑷磋璇婂強寤惰
璇婃柇銆傜敱浜庡奖鍍忓琛ㄧ幇涓庣梾姣掓�ц剳鐐庢瀬鐩镐技
,
涓斿崟绾柋鐤圭梾姣掓�ц剳鐐?/p>
(herpes simplex virus
encephslitis HSE)
鐨勬暎鍙戞�?/p>
,
鏃犲鑺傛�?/p>
,
鏃犲湴鍖烘�?/p>
,
鍙戠梾骞撮緞涓庢�у埆姣斾笌
GC
鏈夋椂鍗佸垎鐩镐技
,
琚瘖鏂负
HSE
杈冧负澶氳銆?/p>
Ginsberg L[2]
绛夋姤閬?/p>
1.5%
鐨勭梾姣掓�ц剳鐐庢椿妫�璇婃柇涓鸿剳鑳惰川鐦ゃ�備絾娌荤枟涓婂樊鍒緝
澶?/p>
,
鎵�浠ラ壌鍒畩涓洪噸瑕?/p>
,
闅忕潃
GC
鐨勯�愭笎琚璇嗐�佸彂鐥呯巼鐨勫鍔犲強鍖诲鐭ヨ瘑鐨勪赴瀵屽拰鍙戝睍
,
閫氳繃鏂?/p>
鐚殑瀛︿範
,
灏嗕粠浠ヤ笅鏂归潰鏉ユ瘮杈冧袱鐥呯殑寮傚悓鐐广�?/p>
1
娴佽鐥呭鍙婂彂鐥呮満鍒?/p>
GC:WHO
瀹氫箟涓轰镜鐘?/p>
2
涓垨
2
涓互涓婅剳鍙剁殑鑳惰川缁嗚優鑲跨槫銆傚父渚靛強鍙屼晶澶ц剳鍗婄悆
,
浜﹀彲绱?/p>
鍙婂箷涓嬬敋鑷宠剨楂?/p>
,
褰掔被涓轰笉鏄庢潵婧愮殑绁炵粡涓婄毊鑲跨槫
,
鍗犲悓鏈熺缁忓鑳氬眰鑲跨槫
0.66%,WHO
鍒嗙被
鈪?/p>
绾?/p>
,
鏂囩尞浠ュ讥婕�ц兌璐ㄧ槫
(diffuse glioma)
鍙婂讥婕�ц兌璐ㄦ瘝缁嗚優鐦?/p>
(diffuse cerebral glioblastosis)
绛夊懡
鍚?/p>
,
杩戝勾璇ョ梾缁熶竴鍛藉悕涓?/p>
鈥淕C鈥?/p>
銆傚彂鐥呭钩鍧囧勾榫勪负
45
宀?/p>
,
鐢峰コ姣斾緥涓?/p>
1.34
锔?/p>
1[3],
涔熸湁鏂囩尞鎶ラ亾涓?/p>
10
锔?/p>
1[4],
骞冲潎鐥呯▼涓?/p>
13
涓湀銆傚垎鍨?/p>
:
鐩墠璁や负鏈変袱绉嶇被鍨嬬殑
GC
銆備竴鍨嬫湁鍏稿瀷琛ㄧ幇
,
鏂扮敓鐗╂蹈娑?/p>
鎬х敓闀?/p>
,
涓斿彈绱殑缁撴瀯鍛堝讥婕�ц偪鑳�
,
娌℃湁鏄庢樉鐨勮偪鐦よ偪鍧楀舰鎴?/p>
;
浜屽瀷鍙兘鏄敱涓�鍨嬪彂灞曡�屾潵
,
闄や簡
寮ユ极鎬ф蹈娑﹀
,
杩樻湁鏄庢樉鐨勮偪鍧?/p>
,
琛ㄧ幇涓烘伓鎬ц偪鐦ょ殑鐗瑰緛銆傝捣婧?/p>
:GC
鐨勮捣婧愭湁璁稿浜夎
,
鏈変簺褰㈡�?/p>
鐗瑰緛涓庢槦褰㈢粏鑳炵槫鐩镐技
,
浣嗕篃鏈変竴浜涜〃鐜颁笉鏀寔杩欎簺瑙傜偣銆傚叧浜庡叾鐥呯悊璧锋簮鏈夎澶氬亣璇?/p>
,
濡傝兌璐?/p>
缁嗚優鑳氳儙鏃跺彂鑲查殰纰嶃�佸讥婕�ф蹈娑︺�佸涓績璧锋簮銆佸師浣嶅娈栦互鍙婃墍璋撶殑鍖哄煙鎬ц浆鍖栫瓑銆傚洜姝?/p>
,
鍙互璁や负
GC
涓虹粍缁囪捣婧愪粛涓嶆槑纭?/p>
,
缁撳悎鏂囩尞澶嶄範
,
璁や负璇ョ梾浠ュ讥婕�х櫧璐ㄦ蹈娑﹀強澶氶儴浣嶅彂鐢熶负
鐗圭偣
[3,4]
銆?/p>
HSE
鏄敱鍗曠函鐤辩柟鐥呮瘨渚靛叆鑴戝唴鎵�鑷寸殑鎬ユ�т腑鏋㈢缁忕郴缁熸劅鏌撱�傚憟鏁ｅ彂鎬с�佹棤瀛ｈ妭